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2018 Vol.31, Issue 6 Preview Page

Research Article

Immune Cells Activity, Cytotoxicity and Nitrite Scavenging Activity of Extracts from Several Resource Plants
Hee-Ock Boo1
,
Jeong-Hun Park2
,
Hyeon-Yong Park3*
1Ph.D. Researcher, Department of Biology, Chosun University
2Master Researcher, Department of Biology, Chosun University
3Professor, Department of Biology, Chosun University
*Corresponding Author
31 December 2018. pp. 604-611
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Abstract

This study was conducted to explore the immune activity, anticancer activity and nitrile scavenging activities of methanol extracts from the various organs of four Korean resource plants. The immune responses from both human T and B cell line was significantly enhanced in the cell growth compared to control while the cell growth was influenced at a certain period of culture. The results revealed that the cell growth of both human T and B cell was altered in a time dependent manner. Among tested several resource plants, the flower extract of E. japonicum demonstrated a pronounced cytotoxicity against HCT-116 cell with an IC50 value 132.08 ㎍ ㎖-1. The flower extract from Corylopsis coreana had a promising scavenging activity against pH 1.2 compared to other species. Taken together, the studied resource plants have influenced significantly in response to immunity and also have the potential cytotoxicity and nitric scavenging activities. However, the species E. japonicum exhibited the pronounced activities from several resource plants. The result from this investigation suggests that the extracts of studied resource plant could be an addition to basic medicine for some diseases.

Keywords
Corylopsis coreana
Cytotoxicity
Erythronium japonicum
Immune activity
Nitrite scavenging activity
Phragmites communis
Salicornia herbacea
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Information
  • Publisher :The Plant Resources Society of Korea
  • Publisher(Ko) :한국자원식물학회
  • Journal Title :Korean Journal of Plant Resources
  • Journal Title(Ko) :한국자원식물학회지
  • Volume : 31
  • No :6
  • Pages :604-611
  • Received Date : 2018-10-19
  • Revised Date : 2018-11-13
  • Accepted Date : 2018-11-14
  • DOI :https://doi.org/10.7732/kjpr.2018.31.6.604
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